Immunosenescence and human vaccine immune responses
نویسندگان
چکیده
منابع مشابه
Successful immunosenescence and the remodelling of immune responses with ageing.
In recent decades, major theoretical and technological advances have been achieved in the field of immunology. These have allowed the scientific community to analyse the immune system in a much more sophisticated manner than was possible even 20 years ago. Moreover, great theoretical changes have also occurred in gerontology-in particular, the hypothesis has been put forward that ageing and dis...
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To determine the naturally occurring immunological responses to the Schistosoma mansoni antigens paramyosin, IrV-5, Sm-23 (MAP-3), and triose phosphate isomerase (MAP-4), a total of 119 subjects from an area of endemicity for schistosomiasis, including "resistant" subjects (n = 17) were evaluated. Specific immunoglobulin G1 (IgG1), IgG2, IgG3, IgG4, and IgA levels for each of the antigens and t...
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Memory formation is the most important aspect of a vaccine which can guarantee long-lasting immunity and protection. The main aim of the present study was to evaluate the memory immune responses after immunization with a mini vaccine. Mice were immunized with human immunodeficiency virus-1 P24-Nef fusion peptide and then cellular and humoral immune responses were evaluated. In order to determin...
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chronic carriers worldwide.1 The highest carrier rate is in Asia and Africa. 2 Chronic infection develops among 90% of newborns, 29-40% of children and 5-10% of adults.3 Patients with long-standing active liver disease are at high risk of developing liver cirrhosis and hepatocellular carcinoma.4 Hepatitis B virus is responsible for 80% of liver cancer cases in the world.5 Therefore, prevention ...
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Background & Objective: DNA vaccines as a new generation of vaccines require adjuvant to improve vaccine immunogenicity; adjuvants can also increase the DNA vaccine efficacy. In this study, the effects of the host’s interferon-inducible Mx protein as bio adjuvant and conventional alum adjuvant were evaluated. Materials & Methods: The BALB/c mice were immunized by different prime-boost strate...
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ژورنال
عنوان ژورنال: Immunity & Ageing
سال: 2019
ISSN: 1742-4933
DOI: 10.1186/s12979-019-0164-9